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Bills vs Panthers head to head

The Bills lead the series 2-0 across the 2 meetings Kelly holds since 2021, playoffs included. Against the closing spread the Bills are 1-0 (1); over/under 1-0 (1). Last 2: Bills 2-0 (2). Latest: Buffalo Bills at Carolina Panthers, Sunday, October 26, 2025 at 1:00 PM ET.

Latest game

Buffalo Bills at Carolina PanthersSunday, October 26, 2025 at 1:00 PM ET · 2025 week 8

Every meeting (2)

Row tabs and the Ask box filter on the engine's side; the record in the status line is counted for the rows in view.

Showing (2) of (2) · Meetings · Compared with the 2 meetings Kelly holds. In view: Bills 2-0-0 (2), ATS 1-0-0 (1), O/U 1-0-0 (1), small sample

GameDateTypeSiteWinnerScoreBills margin
2025 W82025-10-26Regular seasonCarolinaBillsBUF 40, CAR 931
2021 W152021-12-19Regular seasonBuffaloBillsBUF 31, CAR 1417
Total (2)—————48
Per meeting—————24

Data as of 2026-11-13 12:50 UTCSource: nflverse schedules and results (CC BY 4.0), changed by Kelly; closing lines: Kelly's consensus, else nflverse's published close from 1999

Series splits (7)

The series cut by site, season type, closing line, decade and the latest meetings, with the NFL average over the same seasons. Marked rates rest on fewer than 5 decided meetings.

Showing (7) of (7) · Splits · Compared with every meeting (2) and the NFL average

SplitGBills W-L-TBills win %BUF pts/GCAR pts/GBills margin/GPoints/G
Site
At Buffalo11-0-0100%31141745
At Carolina11-0-0100%4093149
Season type
Regular season22-0-0100%35.511.52447
Closing line
Bills favoured11-0-0100%4093149
No closing line11-0-0100%31141745
Decade
2020s22-0-0100%35.511.52447
Recent
Last 2 meetings22-0-0100%35.511.52447
All meetings (2)22-0-0100%35.511.52447
NFL average, 2021 to 20251,424——22.622.6—45.2

Data as of 2026-11-13 12:50 UTCSource: nflverse schedules and results (CC BY 4.0), changed by Kelly; closing lines: Kelly's consensus, else nflverse's published close from 1999

Streaks (4)

The longest runs in the series. Active streaks are still going.

Showing (4) of (4) · Streaks · Sorted by Meetings, high to low · Compared with every meeting Kelly holds (2)

Streak ofMeetingsFromToStateOut of
Bills wins22021 W152025 W8Active2
Home team wins12021 W152021 W15Ended2
Bills covers12025 W82025 W8Active1
Overs12025 W82025 W8Active1

Data as of 2026-11-13 12:50 UTCSource: nflverse schedules and results (CC BY 4.0), changed by Kelly; closing lines: Kelly's consensus, else nflverse's published close from 1999

Postseason meetings (0)

No playoff meeting in the seasons Kelly holds since 2021.

Questions (4)

What is the Bills vs Panthers head-to-head record?
The Bills lead the series 2-0 across the 2 meetings Kelly holds since 2021, playoffs included.
What is the Bills vs Panthers record against the spread?
The Bills are 1-0-0 against the closing spread in the 1 meetings with a line; the Panthers are 0-1-0.
Do Bills vs Panthers games go over the total?
1 overs, 0 unders and 0 pushes against the closing total in the 1 meetings with one.
Who won the last Bills vs Panthers game?
The Bills won 40-9 in Carolina on October 26, 2025.

Data as of 2026-11-13 12:50 UTC · 2 meetings Kelly holds since 2021 · results from nflverse (CC BY 4.0), changed by Kelly; closing lines from Kelly's consensus, else nflverse's published close