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49ers vs Panthers head to head

The 49ers lead the series 3-0 across the 3 meetings Kelly holds since 2019, playoffs included. Against the closing spread the 49ers are 1-0 (1); over/under 0-1 (1). Last 3: 49ers 3-0 (3). Latest: Carolina Panthers at San Francisco 49ers, Monday, November 24, 2025 at 8:15 PM ET.

Latest game

Carolina Panthers at San Francisco 49ersMonday, November 24, 2025 at 8:15 PM ET · 2025 week 12

Every meeting (3)

Row tabs and the Ask box filter on the engine's side; the record in the status line is counted for the rows in view.

Showing (3) of (3) · Meetings · Compared with the 3 meetings Kelly holds. In view: 49ers 3-0-0 (3), ATS 1-0-0 (1), O/U 0-1-0 (1), small sample

GameDateTypeSiteWinnerScore49ers margin
2025 W122025-11-24Regular seasonSan Francisco49ersSF 20, CAR 911
2022 W52022-10-09Regular seasonCarolina49ersSF 37, CAR 1522
2019 W82019-10-27Regular seasonSan Francisco49ersSF 51, CAR 1338
Total (3)—————71
Per meeting—————23.7

Data as of 2026-11-15 11:08 UTCSource: nflverse schedules and results (CC BY 4.0), changed by Kelly; closing lines: Kelly's consensus, else nflverse's published close from 1999

Series splits (8)

The series cut by site, season type, closing line, decade and the latest meetings, with the NFL average over the same seasons. Marked rates rest on fewer than 5 decided meetings.

Showing (8) of (8) · Splits · Compared with every meeting (3) and the NFL average

SplitG49ers W-L-T49ers win %SF pts/GCAR pts/G49ers margin/GPoints/G
Site
At San Francisco22-0-0100%35.51124.546.5
At Carolina11-0-0100%37152252
Season type
Regular season33-0-0100%3612.323.748.3
Closing line
49ers favoured11-0-0100%2091129
No closing line22-0-0100%44143058
Decade
2020s22-0-0100%28.51216.540.5
2010s11-0-0100%51133864
Recent
Last 3 meetings33-0-0100%3612.323.748.3
All meetings (3)33-0-0100%3612.323.748.3
NFL average, 2019 to 20251,960——22.922.9—45.8

Data as of 2026-11-15 11:08 UTCSource: nflverse schedules and results (CC BY 4.0), changed by Kelly; closing lines: Kelly's consensus, else nflverse's published close from 1999

Streaks (5)

The longest runs in the series. Active streaks are still going.

Showing (5) of (5) · Streaks · Sorted by Meetings, high to low · Compared with every meeting Kelly holds (3)

Streak ofMeetingsFromToStateOut of
49ers wins32019 W82025 W12Active3
Home team wins12025 W122025 W12Active3
Home team wins12019 W82019 W8Ended3
49ers covers12025 W122025 W12Active1
Unders12025 W122025 W12Active1

Data as of 2026-11-15 11:08 UTCSource: nflverse schedules and results (CC BY 4.0), changed by Kelly; closing lines: Kelly's consensus, else nflverse's published close from 1999

Postseason meetings (0)

No playoff meeting in the seasons Kelly holds since 2019.

Questions (4)

What is the 49ers vs Panthers head-to-head record?
The 49ers lead the series 3-0 across the 3 meetings Kelly holds since 2019, playoffs included.
What is the 49ers vs Panthers record against the spread?
The 49ers are 1-0-0 against the closing spread in the 1 meetings with a line; the Panthers are 0-1-0.
Do 49ers vs Panthers games go over the total?
0 overs, 1 unders and 0 pushes against the closing total in the 1 meetings with one.
Who won the last 49ers vs Panthers game?
The 49ers won 20-9 in San Francisco on November 24, 2025.

Data as of 2026-11-15 11:08 UTC · 3 meetings Kelly holds since 2019 · results from nflverse (CC BY 4.0), changed by Kelly; closing lines from Kelly's consensus, else nflverse's published close