Jaguars 26, 49ers 21
Final: Jaguars 26, 49ers 21 at Levi's Stadium. The Jaguars covered the closing spread (49ers −3.5). 47 points went over the 45.5 closing total.
- Jaguars
- 26
- 49ers
- 21
- Closing spread
- 49ers −3.549ers missed
- Closing total
- 45.5Over
Line score (2)
Showing (2) of (2) · This game
| Team | Final | Close | ATS | Total | O/U |
|---|---|---|---|---|---|
| Jacksonville Jaguars | 26 | 3.5 | Covered | 45.5 | Over |
| San Francisco 49ers | 21 | -3.5 | Missed | 45.5 | Over |
Data as of 2026-11-14Source: Data from nflverse (CC BY 4.0), changed by Kelly; Closing lines: Kelly consensus close, else nflverse's published close
Team comparison (0)
The engine didn’t answer for the team comparison; it shows when it does.
Points, third-down and red-zone rates, penalties and ATS beside the ranks wait for the engine’s game.team_compare view.
Unit against unit (0)
The engine didn’t answer for unit against unit.
Injuries (21)
Showing (21) of (21) · Latest team reports
| Player | Team | Pos | Status | Injury | Practice | Changed |
|---|---|---|---|---|---|---|
| Alfred Collins | SF | DT | Injured reserve | — | — | — |
| Andrew Farmer II | SF | LB | Injured reserve | — | — | — |
| Anton Harrison | JAX | OT | Injured reserve | — | — | — |
| C.J. West | SF | DT | Injured reserve | — | — | — |
| Caleb Ransaw | JAX | SAF | Injured reserve | — | — | — |
| Carter Bradley | JAX | QB | Injured reserve | — | — | — |
| Christian Kirk | SF | WR | Injured reserve | — | — | — |
| DaVon Hamilton | JAX | DT | Injured reserve | — | — | — |
| Darrick Forrest | SF | SAF | Injured reserve | — | — | — |
| De'Zhaun Stribling | SF | WR | Injured reserve | — | — | — |
| Eric Murray | JAX | S | Injured reserve | — | — | — |
| Garrett DiGiorgio | JAX | OT | Injured reserve | — | — | — |
| Jake Tonges | SF | TE | Injured reserve | — | — | — |
| Jared Bartlett | JAX | LB | Injured reserve | — | — | — |
| Mikail Kamara | SF | DE | Injured reserve | — | — | — |
| Nick Martin | SF | LB | Injured reserve | — | — | — |
| Nick Zakelj | SF | OT | Injured reserve | — | — | — |
| Parker Hughes | JAX | LB | Injured reserve | — | — | — |
| Ricky Pearsall | SF | WR | Injured reserve | — | — | — |
| Sam Mustipher | JAX | C | Injured reserve | — | — | — |
| Sam Okuayinonu | SF | DT | Injured reserve | — | — | — |
Source: Injury status from team reports
Questions (4)
Who won Jaguars vs 49ers?
Jaguars 26, 49ers 21 at Levi's Stadium on Sunday, September 28, 2025.
Did the Jaguars cover the spread?
Yes. The closing spread was 49ers −3.5 at Kelly's consensus.
Did Jaguars vs 49ers go over the total?
Yes. 47 points against a 45.5 closing total.
What is the Jaguars vs 49ers all-time record?
The 49ers lead 2-1 in the (3) meetings Kelly holds, playoffs included.