Vikings at 49ers
The 49ers (7-1) are 3.5-point favourites at home against the Vikings (6-2) on Sunday, November 22, 2026 at 8:20 PM ET, with a total of 45.5. That implies Vikings 21, 49ers 24.5. The no-vig moneyline gives the 49ers a 66.2% win chance.
- Spread
- 49ers −3.5Open −3.5
- Total
- 45.5Open 45.5
- Moneyline
- Vikings +175 · 49ers −213No-vig 33.8% · 66.2%
- Implied score
- Vikings 21 · 49ers 24.5
- Kickoff
- Sunday, November 22, 2026 at 8:20 PM ETEstadio Banorte
Team comparison (2)
Showing (2) of (2) · Totals · Compared with NFL teams in the same season
| Team | Games played | EPA per play | Success rate | EPA per play allowed | Success rate allowed | Passing yards | Rushing yards | Sacks | Interceptions caught | Fumbles lost |
|---|---|---|---|---|---|---|---|---|---|---|
| San Francisco 49ers | 53 | 0.2062 | 0.5251 | — | — | — | — | — | — | — |
| Minnesota Vikings | 53 | -0.10328 | 0.35732 | — | — | — | — | — | — | — |
| League average | 5 | 0.007094 | 0.434 | — | — | — | — | — | — | — |
Data as of 2026-11-14Source: nflverse data (CC BY 4.0)Each season's line from the source Kelly serves first by precedence (nflverse, kelly, balldontlie, cfbd), else the sum of its games.At least 1 games (min_sample).Stat catalogue 1.0.0; a missing value is not zero, and games without it are left out of its total.
Points, third-down and red-zone rates, penalties and ATS beside the ranks wait for the engine’s game.team_compare view.
Unit against unit (10)
Showing (10) of (10) · This season, ranks of 32 · Compared with NFL teams in the same season
| Stat | Offense | Off rank | Defense faced | Def rank | NFL avg | Rank gap |
|---|---|---|---|---|---|---|
| Vikings offense against 49ers defense | ||||||
| EPA per play | -0.103 | 28 | — | — | 0.007094 | Locked |
| Success rate | 0.357 | 32 | — | — | 0.434406 | Locked |
| Explosiveness | — | — | — | — | — | Locked |
| Pass EPA per play | — | — | — | — | — | Locked |
| Rush EPA per play | — | — | — | — | — | Locked |
| 49ers offense against Vikings defense | ||||||
| EPA per play | 0.206 | 2 | — | — | 0.007094 | Locked |
| Success rate | 0.525 | 1 | — | — | 0.434406 | Locked |
| Explosiveness | — | — | — | — | — | Locked |
| Pass EPA per play | — | — | — | — | — | Locked |
| Rush EPA per play | — | — | — | — | — | Locked |
Data as of 2026-11-14Each season's line from the source Kelly serves first by precedence (nflverse, kelly, balldontlie, cfbd), else the sum of its games.At least 1 games (min_sample).Stat catalogue 1.0.0; a missing value is not zero, and games without it are left out of its total.
Injuries (18)
Showing (18) of (18) · Latest team reports
| Player | Team | Pos | Status | Injury | Practice | Changed |
|---|---|---|---|---|---|---|
| Alfred Collins | SF | DT | Injured reserve | — | — | — |
| Andrew Farmer II | SF | LB | Injured reserve | — | — | — |
| C.J. West | SF | DT | Injured reserve | — | — | — |
| Christian Kirk | SF | WR | Injured reserve | — | — | — |
| Darrick Forrest | SF | SAF | Injured reserve | — | — | — |
| De'Zhaun Stribling | SF | WR | Injured reserve | — | — | — |
| Demond Claiborne | MIN | RB | Injured reserve | — | — | — |
| Donovan Jackson | MIN | G | Injured reserve | — | — | — |
| Jake Tonges | SF | TE | Injured reserve | — | — | — |
| Jamal Adams | MIN | LB | Injured reserve | — | — | — |
| Josh Oliver | MIN | TE | Injured reserve | — | — | — |
| Mikail Kamara | SF | DE | Injured reserve | — | — | — |
| Nick Martin | SF | LB | Injured reserve | — | — | — |
| Nick Samac | MIN | C | Injured reserve | — | — | — |
| Nick Zakelj | SF | OT | Injured reserve | — | — | — |
| Ricky Pearsall | SF | WR | Injured reserve | — | — | — |
| Sam Okuayinonu | SF | DT | Injured reserve | — | — | — |
| Tyler Batty | MIN | LB | Injured reserve | — | — | — |
Source: Injury status from team reports
Questions (6)
What is the spread for Vikings vs 49ers?
49ers −3.5 at Kelly's consensus of US sportsbooks, after opening at −3.5. The total is 45.5.
Who is favoured, Vikings or 49ers?
The 49ers, at −213 on the moneyline: a 66.2% win chance once the sportsbook margin is removed.
When is Vikings vs 49ers?
Sunday, November 22, 2026 at 8:20 PM ET at Estadio Banorte.
Who is injured for Vikings vs 49ers?
Nobody is listed out on the latest team reports.
Who won the last Vikings-49ers game?
The Vikings, 23-17 on Sunday, September 15, 2024.
What is the Vikings vs 49ers all-time record?
The series is level at 2-2 in the (4) meetings Kelly holds.